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Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling
BACKGROUND: Our previous study showed Musashi2 (MSI2) promoted chemotherapy resistance and pernicious biology of pancreatic cancer (PC) by down-regulating Numb and p53. We further explored the novel molecular mechanism involving its oncogenic role in PC development. METHODS: We investigated the pote...
Autores principales: | Sheng, Weiwei, Shi, Xiaoyang, Lin, Yiheng, Tang, Jingtong, Jia, Chao, Cao, Rongxian, Sun, Jian, Wang, Guosen, Zhou, Lei, Dong, Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6967093/ https://www.ncbi.nlm.nih.gov/pubmed/31952541 http://dx.doi.org/10.1186/s13046-020-1521-4 |
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