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Identification of signature genes associated with therapeutic resistance to anti-VEGF therapy

VEGF-mediated tumor angiogenesis is a validated clinical target in many cancers, but modest efficacy and rapid development of resistance are major challenges of VEGF-targeted therapies. To establish a molecular signature of this resistance in ovarian cancer, we developed preclinical tumor models of...

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Detalles Bibliográficos
Autores principales: Jaiprasart, Pharavee, Dogra, Samrita, Neelakantan, Deepika, Devapatla, Bharat, Woo, Sukyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6967771/
https://www.ncbi.nlm.nih.gov/pubmed/32002127
http://dx.doi.org/10.18632/oncotarget.27307