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Tools for Assessing the Protective Efficacy of TB Vaccines in Humans: in vitro Mycobacterial Growth Inhibition Predicts Outcome of in vivo Mycobacterial Infection

Tuberculosis (TB) remains a leading global cause of morbidity and mortality and an effective new vaccine is urgently needed. A major barrier to the rational development of novel TB vaccines is the lack of a validated immune correlate or biomarker of protection. Mycobacterial Growth Inhibition Assays...

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Detalles Bibliográficos
Autores principales: Tanner, Rachel, Satti, Iman, Harris, Stephanie A., O'Shea, Matthew K., Cizmeci, Deniz, O'Connor, Daniel, Chomka, Agnieszka, Matsumiya, Magali, Wittenberg, Rachel, Minassian, Angela M., Meyer, Joel, Fletcher, Helen A., McShane, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968127/
https://www.ncbi.nlm.nih.gov/pubmed/31998295
http://dx.doi.org/10.3389/fimmu.2019.02983