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The potassium transporter KdpA affects persister formation by regulating ATP levels in Mycobacterium marinum

Mycobacterial persistence mechanisms remain to be fully characterized. Screening a transposon insertion library of Mycobacterium marinum identified kdpA, whose inactivation reduced the fraction of persisters after exposure to rifampicin. kdpA encodes a transmembrane protein that is part of the Kdp-A...

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Detalles Bibliográficos
Autores principales: Liu, Xiaofan, Wang, Chuan, Yan, Bo, Lyu, Liangdong, Takiff, Howard E., Gao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968386/
https://www.ncbi.nlm.nih.gov/pubmed/31913766
http://dx.doi.org/10.1080/22221751.2019.1710090