An analysis of abnormalities in the B cell receptor repertoire in patients with systemic sclerosis using high-throughput sequencing

Systemic sclerosis is a chronic multisystem autoimmune disease that is associated with polyclonal B cell hyperreactivity. The CDR3 of BCRs is the major site of antigen recognition. Therefore, we analyzed the BCR repertoire of patients with SSc. The BCR repertoires in 12 subjects including eight SSc...

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Detalles Bibliográficos
Autores principales: Shi, Xiaodong, Shao, Tihong, Huo, Feifei, Zheng, Chenqing, Li, Wanyu, Jiang, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968515/
https://www.ncbi.nlm.nih.gov/pubmed/31988805
http://dx.doi.org/10.7717/peerj.8370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968515/
https://www.ncbi.nlm.nih.gov/pubmed/31988805
http://dx.doi.org/10.7717/peerj.8370

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