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Methyl lucidone induces apoptosis and G(2)/M phase arrest via the PI3K/Akt/NF-κB pathway in ovarian cancer cells

CONTEXT: Methyl lucidone (ML) from the dried fruit of Lindera erythrocarpa Makino (Lauraceae) exhibits cytotoxic effects in various cancer cell lines. However, its effects on ovarian cancer cells remain unknown. OBJECTIVE: This study evaluates the mechanism of ML-induced apoptosis, cell cycle distri...

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Detalles Bibliográficos
Autores principales: Yoon, Jae-Hwan, Shin, Jong-Woon, Pham, Thu-Huyen, Choi, Youn-Jin, Ryu, Hyung-Won, Oh, Sei-Ryang, Oh, Jae-Wook, Yoon, Do-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968553/
https://www.ncbi.nlm.nih.gov/pubmed/31875458
http://dx.doi.org/10.1080/13880209.2019.1701044