N-monoarylacetothioureas as potent urease inhibitors: synthesis, SAR, and biological evaluation

A urease inhibitor with good in vivo profile is considered as an alternative agent for treating infections caused by urease-producing bacteria such as Helicobacter pylori. Here, we report a series of N-monosubstituted thioureas, which act as effective urease inhibitors with very low cytotoxicity. On...

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Detalles Bibliográficos
Autores principales: Li, Wei-Yi, Ni, Wei-Wei, Ye, Ya-Xi, Fang, Hai-Lian, Pan, Xing-Ming, He, Jie-Ling, Zhou, Tian-Li, Yi, Juan, Liu, Shan-Shan, Zhou, Mi, Xiao, Zhu-Ping, Zhu, Hai-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968641/
https://www.ncbi.nlm.nih.gov/pubmed/31880473
http://dx.doi.org/10.1080/14756366.2019.1706503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968641/
https://www.ncbi.nlm.nih.gov/pubmed/31880473
http://dx.doi.org/10.1080/14756366.2019.1706503

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