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Mechanisms of increased bioavailability through amorphous solid dispersions: a review

Amorphous solid dispersions (ASDs) can increase the oral bioavailability of poorly soluble drugs. However, their use in drug development is comparably rare due to a lack of basic understanding of mechanisms governing drug liberation and absorption in vivo. Furthermore, the lack of a unified nomencla...

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Detalles Bibliográficos
Autores principales: Schittny, Andreas, Huwyler, Jörg, Puchkov, Maxim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968646/
https://www.ncbi.nlm.nih.gov/pubmed/31885288
http://dx.doi.org/10.1080/10717544.2019.1704940