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Binding of the von Willebrand Factor A Domain of Capillary Morphogenesis Protein 2 to Anthrax Protective Antigen Vaccine Reduces Immunogenicity in Mice

Protective antigen (PA) is a component of anthrax toxin that can elicit toxin-neutralizing antibody responses. PA is also the major antigen in the current vaccine to prevent anthrax, but stability problems with recombinant proteins have complicated the development of new vaccines containing recombin...

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Detalles Bibliográficos
Autores principales: de Oliveira, Fabiana Freire Mendes, Mamillapalli, Sireesha, Gonti, Srinivas, Brey, Robert N., Li, Han, Schiffer, Jarad, Casadevall, Arturo, Bann, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968648/
https://www.ncbi.nlm.nih.gov/pubmed/31941807
http://dx.doi.org/10.1128/mSphere.00556-19