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Binding of the von Willebrand Factor A Domain of Capillary Morphogenesis Protein 2 to Anthrax Protective Antigen Vaccine Reduces Immunogenicity in Mice
Protective antigen (PA) is a component of anthrax toxin that can elicit toxin-neutralizing antibody responses. PA is also the major antigen in the current vaccine to prevent anthrax, but stability problems with recombinant proteins have complicated the development of new vaccines containing recombin...
Autores principales: | de Oliveira, Fabiana Freire Mendes, Mamillapalli, Sireesha, Gonti, Srinivas, Brey, Robert N., Li, Han, Schiffer, Jarad, Casadevall, Arturo, Bann, James G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968648/ https://www.ncbi.nlm.nih.gov/pubmed/31941807 http://dx.doi.org/10.1128/mSphere.00556-19 |
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