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Dual and Triple Epithelial Coculture Model Systems with Donor-Derived Microbiota and THP-1 Macrophages To Mimic Host-Microbe Interactions in the Human Sinonasal Cavities

The epithelium of the human sinonasal cavities is colonized by a diverse microbial community, modulating epithelial development and immune priming and playing a role in respiratory disease. Here, we present a novel in vitro approach enabling a 3-day coculture of differentiated Calu-3 respiratory epi...

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Detalles Bibliográficos
Autores principales: De Rudder, Charlotte, Calatayud Arroyo, Marta, Lebeer, Sarah, Van de Wiele, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968656/
https://www.ncbi.nlm.nih.gov/pubmed/31941815
http://dx.doi.org/10.1128/mSphere.00916-19