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Dual and Triple Epithelial Coculture Model Systems with Donor-Derived Microbiota and THP-1 Macrophages To Mimic Host-Microbe Interactions in the Human Sinonasal Cavities
The epithelium of the human sinonasal cavities is colonized by a diverse microbial community, modulating epithelial development and immune priming and playing a role in respiratory disease. Here, we present a novel in vitro approach enabling a 3-day coculture of differentiated Calu-3 respiratory epi...
Autores principales: | De Rudder, Charlotte, Calatayud Arroyo, Marta, Lebeer, Sarah, Van de Wiele, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968656/ https://www.ncbi.nlm.nih.gov/pubmed/31941815 http://dx.doi.org/10.1128/mSphere.00916-19 |
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