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OCTN2-targeted nanoparticles for oral delivery of paclitaxel: differential impact of the polyethylene glycol linker size on drug delivery in vitro, in situ, and in vivo

Targeted nanocarriers have shown great promise in drug delivery because of optimized drug behavior and improved therapeutic efficacy. How to improve the targeting efficiency of nanocarriers for the maximum possible drug delivery is a critical issue. Here we developed L-carnitine-conjugated nanoparti...

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Detalles Bibliográficos
Autores principales: Kou, Longfa, Sun, Rui, Xiao, Shuyi, Cui, Xiao, Sun, Jin, Ganapathy, Vadivel, Yao, Qing, Chen, Ruijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968687/
https://www.ncbi.nlm.nih.gov/pubmed/31913724
http://dx.doi.org/10.1080/10717544.2019.1710623