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Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors

The selectivity for a specific human Carbonic Anhydrase (hCA) isoform is an important property a hCA inhibitor (CAI) should be endowed with, in order to constitute a valuable therapeutic tool for the treatment of a desired pathology. In this context, we developed a chemoinformatic platform that allo...

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Detalles Bibliográficos
Autores principales: Poli, Giulio, Galati, Salvatore, Martinelli, Adriano, Supuran, Claudiu T., Tuccinardi, Tiziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968703/
https://www.ncbi.nlm.nih.gov/pubmed/31854205
http://dx.doi.org/10.1080/14756366.2019.1705291