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Sequence conservation of mitochondrial (mt)DNA during expansion of clonal mammary epithelial populations suggests a common mtDNA template in CzechII mice

One major foundation of cancer etiology is the process of clonal expansion. The mechanisms underlying the complex process of a single cell leading to a clonal dominant tumor, are poorly understood. Our study aims to analyze mitochondrial DNA (mtDNA) for somatic single nucleotide polymorphisms (SNPs)...

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Detalles Bibliográficos
Autores principales: Johnson, Jabril R., Lack, Justin B., Boulanger, Corinne A., Ragle, Lauren E., Smith, Gilbert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968779/
https://www.ncbi.nlm.nih.gov/pubmed/32010429
http://dx.doi.org/10.18632/oncotarget.27429