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Sequence conservation of mitochondrial (mt)DNA during expansion of clonal mammary epithelial populations suggests a common mtDNA template in CzechII mice
One major foundation of cancer etiology is the process of clonal expansion. The mechanisms underlying the complex process of a single cell leading to a clonal dominant tumor, are poorly understood. Our study aims to analyze mitochondrial DNA (mtDNA) for somatic single nucleotide polymorphisms (SNPs)...
Autores principales: | Johnson, Jabril R., Lack, Justin B., Boulanger, Corinne A., Ragle, Lauren E., Smith, Gilbert H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968779/ https://www.ncbi.nlm.nih.gov/pubmed/32010429 http://dx.doi.org/10.18632/oncotarget.27429 |
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