Modeling the effect of prolonged ethanol exposure on global gene expression and chromatin accessibility in normal 3D colon organoids

In this study we aimed to explore the potential biological effect of ethanol exposure on healthy colon epithelial cells using normal human colon 3D organoid “mini-gut” cultures. In numerous published studies ethanol use has been shown to be an environmental risk factor for colorectal cancer (CRC) de...

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Detalles Bibliográficos
Autores principales: Devall, Matthew, Jennelle, Lucas T., Bryant, Jennifer, Bien, Stephanie, Peters, Ulrike, Powell, Steven, Casey, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968849/
https://www.ncbi.nlm.nih.gov/pubmed/31951625
http://dx.doi.org/10.1371/journal.pone.0227116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968849/
https://www.ncbi.nlm.nih.gov/pubmed/31951625
http://dx.doi.org/10.1371/journal.pone.0227116

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