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CNP mediated selective toxicity on melanoma cells is accompanied by mitochondrial dysfunction

Cerium (Ce) oxide nanoparticles (CNP; nanoceria) are reported to have cytotoxic effects on certain cancerous cell lines, while at the same concentration they show no cytotoxicity on normal (healthy) cells. Redox-active CNP exhibit both selective prooxidative as well as antioxidative properties. The...

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Detalles Bibliográficos
Autores principales: Aplak, Elif, von Montfort, Claudia, Haasler, Lisa, Stucki, David, Steckel, Bodo, Reichert, Andreas S., Stahl, Wilhelm, Brenneisen, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968876/
https://www.ncbi.nlm.nih.gov/pubmed/31951630
http://dx.doi.org/10.1371/journal.pone.0227926