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The GTPase Nog1 co-ordinates the assembly, maturation and quality control of distant ribosomal functional centers

Eukaryotic ribosome precursors acquire translation competence in the cytoplasm through stepwise release of bound assembly factors, and proofreading of their functional centers. In case of the pre-60S, these steps include removal of placeholders Rlp24, Arx1 and Mrt4 that prevent premature loading of...

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Detalles Bibliográficos
Autores principales: Klingauf-Nerurkar, Purnima, Gillet, Ludovic C, Portugal-Calisto, Daniela, Oborská-Oplová, Michaela, Jäger, Martin, Schubert, Olga T, Pisano, Agnese, Peña, Cohue, Rao, Sanjana, Altvater, Martin, Chang, Yiming, Aebersold, Ruedi, Panse, Vikram G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968927/
https://www.ncbi.nlm.nih.gov/pubmed/31909713
http://dx.doi.org/10.7554/eLife.52474