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Biophysical and biomolecular interactions of malaria-infected erythrocytes in engineered human capillaries

Microcirculatory obstruction is a hallmark of severe malaria, but mechanisms of parasite sequestration are only partially understood. Here, we developed a robust three-dimensional microvessel model that mimics the arteriole-capillary-venule (ACV) transition consisting of a narrow 5- to 10-μm-diamete...

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Detalles Bibliográficos
Autores principales: Arakawa, Christopher, Gunnarsson, Celina, Howard, Caitlin, Bernabeu, Maria, Phong, Kiet, Yang, Eric, DeForest, Cole A., Smith, Joseph D., Zheng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968943/
https://www.ncbi.nlm.nih.gov/pubmed/32010773
http://dx.doi.org/10.1126/sciadv.aay7243