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Biophysical and biomolecular interactions of malaria-infected erythrocytes in engineered human capillaries
Microcirculatory obstruction is a hallmark of severe malaria, but mechanisms of parasite sequestration are only partially understood. Here, we developed a robust three-dimensional microvessel model that mimics the arteriole-capillary-venule (ACV) transition consisting of a narrow 5- to 10-μm-diamete...
Autores principales: | Arakawa, Christopher, Gunnarsson, Celina, Howard, Caitlin, Bernabeu, Maria, Phong, Kiet, Yang, Eric, DeForest, Cole A., Smith, Joseph D., Zheng, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6968943/ https://www.ncbi.nlm.nih.gov/pubmed/32010773 http://dx.doi.org/10.1126/sciadv.aay7243 |
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