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Dexmedetomidine alleviates insulin resistance in hepatocytes by reducing endoplasmic reticulum stress

PURPOSE: Dexmedetomidine (DEX) stabilizes intraoperative blood glucose levels and reduces insulin resistance (IR), a common perioperative complication. However, the molecular mechanisms underlying these effects remain unclear. Since endoplasmic reticulum stress (ERS) is a mechanism of IR, this study...

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Detalles Bibliográficos
Autores principales: Liu, Fanfan, Zhu, Shaojun, Ni, Lifeng, Huang, Ling’er, Wang, Kuirong, Zhou, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969002/
https://www.ncbi.nlm.nih.gov/pubmed/31679138
http://dx.doi.org/10.1007/s12020-019-02118-1