Bacterial Hsp70 resolves misfolded states and accelerates productive folding of a multi-domain protein

The ATP-dependent Hsp70 chaperones (DnaK in E. coli) mediate protein folding in cooperation with J proteins and nucleotide exchange factors (E. coli DnaJ and GrpE, respectively). The Hsp70 system prevents protein aggregation and increases folding yields. Whether it also enhances the rate of folding...

Descripción completa

Detalles Bibliográficos
Autores principales: Imamoglu, Rahmi, Balchin, David, Hayer-Hartl, Manajit, Hartl, F. Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969021/
https://www.ncbi.nlm.nih.gov/pubmed/31953415
http://dx.doi.org/10.1038/s41467-019-14245-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969021/
https://www.ncbi.nlm.nih.gov/pubmed/31953415
http://dx.doi.org/10.1038/s41467-019-14245-4

Ejemplares similares