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Quantitation of deoxynucleoside triphosphates by click reactions

The levels of the four deoxynucleoside triphosphates (dNTPs) are under strict control in the cell, as improper or imbalanced dNTP pools may lead to growth defects and oncogenesis. Upon treatment of cancer cells with therapeutic agents, changes in the canonical dNTPs levels may provide critical infor...

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Detalles Bibliográficos
Autores principales: Huang, Chang-Yu, Yagüe-Capilla, Miriam, González-Pacanowska, Dolores, Chang, Zee-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969045/
https://www.ncbi.nlm.nih.gov/pubmed/31953472
http://dx.doi.org/10.1038/s41598-020-57463-3