5-hydroxymethylcytosine and gene activity in mouse intestinal differentiation

Cytosine hydroxymethylation (5hmC) in mammalian DNA is the product of oxidation of methylated cytosines (5mC) by Ten-Eleven-Translocation (TET) enzymes. While it has been shown that the TETs influence 5mC metabolism, pluripotency and differentiation during early embryonic development, the functional...

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Detalles Bibliográficos
Autores principales: Uribe-Lewis, Santiago, Carroll, Thomas, Menon, Suraj, Nicholson, Anna, Manasterski, Piotr J., Winton, Douglas J., Buczacki, Simon J. A., Murrell, Adele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969059/
https://www.ncbi.nlm.nih.gov/pubmed/31953501
http://dx.doi.org/10.1038/s41598-019-57214-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969059/
https://www.ncbi.nlm.nih.gov/pubmed/31953501
http://dx.doi.org/10.1038/s41598-019-57214-z

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