Reduced Expression of Genes Regulating Cohesion Induces Chromosome Instability that May Promote Cancer and Impact Patient Outcomes

Chromosome instability (CIN), or continual changes in chromosome complements, is an enabling feature of cancer; however, the molecular determinants of CIN remain largely unknown. Emerging data now suggest that aberrant sister chromatid cohesion may induce CIN and contribute to cancer. To explore thi...

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Detalles Bibliográficos
Autores principales: Leylek, Tarik R., Jeusset, Lucile M., Lichtensztejn, Zelda, McManus, Kirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969069/
https://www.ncbi.nlm.nih.gov/pubmed/31953484
http://dx.doi.org/10.1038/s41598-020-57530-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969069/
https://www.ncbi.nlm.nih.gov/pubmed/31953484
http://dx.doi.org/10.1038/s41598-020-57530-9

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