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The mitochondrial negative regulator MCJ modulates the interplay between microbiota and the host during ulcerative colitis

Recent evidences indicate that mitochondrial genes and function are decreased in active ulcerative colitis (UC) patients, in particular, the activity of Complex I of the electron transport chain is heavily compromised. MCJ is a mitochondrial inner membrane protein identified as a natural inhibitor o...

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Detalles Bibliográficos
Autores principales: Pascual-Itoiz, Miguel Angel, Peña-Cearra, Ainize, Martín-Ruiz, Itziar, Lavín, José Luis, Simó, Carolina, Rodríguez, Héctor, Atondo, Estibaliz, Flores, Juana María, Carreras-González, Ana, Tomás-Cortázar, Julen, Barriales, Diego, Palacios, Ainhoa, García-Cañas, Virginia, Pellón, Aize, Fullaondo, Asier, Aransay, Ana Mª, Prados-Rosales, Rafael, Martín, Rebeca, Anguita, Juan, Abecia, Leticia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969106/
https://www.ncbi.nlm.nih.gov/pubmed/31953445
http://dx.doi.org/10.1038/s41598-019-57348-0