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A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment

CRISPR-based gene drives can spread through wild populations by biasing their own transmission above the 50% value predicted by Mendelian inheritance. These technologies offer population-engineering solutions for combating vector-borne diseases, managing crop pests, and supporting ecosystem conserva...

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Detalles Bibliográficos
Autores principales: López Del Amo, Víctor, Bishop, Alena L., Sánchez C., Héctor M., Bennett, Jared B., Feng, Xuechun, Marshall, John M., Bier, Ethan, Gantz, Valentino M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969112/
https://www.ncbi.nlm.nih.gov/pubmed/31953404
http://dx.doi.org/10.1038/s41467-019-13977-7