TLR3 agonists induce fibronectin aggregation by activated astrocytes: a role of pro-inflammatory cytokines and fibronectin splice variants

Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system which eventually results in axonal loss mainly due to failure of remyelination. Previously we have shown that the persistent presence of stable astrocyte-derived fibronectin aggregates in MS lesions impairs OPC...

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Detalles Bibliográficos
Autores principales: Werkman, Inge, Sikkema, Arend H., Versluijs, Joris B., Qin, Jing, de Boer, Pascal, Baron, Wia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969115/
https://www.ncbi.nlm.nih.gov/pubmed/31953424
http://dx.doi.org/10.1038/s41598-019-57069-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969115/
https://www.ncbi.nlm.nih.gov/pubmed/31953424
http://dx.doi.org/10.1038/s41598-019-57069-4

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