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TLR3 agonists induce fibronectin aggregation by activated astrocytes: a role of pro-inflammatory cytokines and fibronectin splice variants
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system which eventually results in axonal loss mainly due to failure of remyelination. Previously we have shown that the persistent presence of stable astrocyte-derived fibronectin aggregates in MS lesions impairs OPC...
Autores principales: | Werkman, Inge, Sikkema, Arend H., Versluijs, Joris B., Qin, Jing, de Boer, Pascal, Baron, Wia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969115/ https://www.ncbi.nlm.nih.gov/pubmed/31953424 http://dx.doi.org/10.1038/s41598-019-57069-4 |
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