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TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh

Milk lipid secretion is a critical process for the delivery of nutrition and energy from parent to offspring. However, the underlying molecular mechanism is less clear. Here we report that TDP-43, a RNA-binding protein, underwent positive selection in the mammalian lineage. Furthermore, TDP-43 gene...

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Detalles Bibliográficos
Autores principales: Zhao, Limin, Ke, Hao, Xu, Haibo, Wang, Guo-Dong, Zhang, Honglei, Zou, Li, Xiang, Shu, Li, Mengyuan, Peng, Li, Zhou, Mingfang, Li, Lingling, Ao, Lei, Yang, Qin, Shen, Che-Kun James, Yi, Ping, Wang, Lu, Jiao, Baowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969145/
https://www.ncbi.nlm.nih.gov/pubmed/31953403
http://dx.doi.org/10.1038/s41467-019-14183-1