Large-scale Analyses of Disease Biomarkers and Apremilast Pharmacodynamic Effects

Finding biomarkers that provide shared link between disease severity, drug-induced pharmacodynamic effects and response status in human trials can provide number of values for patient benefits: elucidating current therapeutic mechanism-of-action, and, back-translating to fast-track development of ne...

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Detalles Bibliográficos
Autores principales: Medvedeva, Irina V., Stokes, Matthew E., Eisinger, Dominic, LaBrie, Samuel T., Ai, Jing, Trotter, Matthew W. B., Schafer, Peter, Yang, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969165/
https://www.ncbi.nlm.nih.gov/pubmed/31953524
http://dx.doi.org/10.1038/s41598-020-57542-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969165/
https://www.ncbi.nlm.nih.gov/pubmed/31953524
http://dx.doi.org/10.1038/s41598-020-57542-5

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