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Large-scale Analyses of Disease Biomarkers and Apremilast Pharmacodynamic Effects
Finding biomarkers that provide shared link between disease severity, drug-induced pharmacodynamic effects and response status in human trials can provide number of values for patient benefits: elucidating current therapeutic mechanism-of-action, and, back-translating to fast-track development of ne...
Autores principales: | Medvedeva, Irina V., Stokes, Matthew E., Eisinger, Dominic, LaBrie, Samuel T., Ai, Jing, Trotter, Matthew W. B., Schafer, Peter, Yang, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969165/ https://www.ncbi.nlm.nih.gov/pubmed/31953524 http://dx.doi.org/10.1038/s41598-020-57542-5 |
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