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A transcriptome-wide antitermination mechanism sustaining identity of embryonic stem cells

Eukaryotic gene expression relies on extensive crosstalk between transcription and RNA processing. Changes in this composite regulation network may provide an important means for shaping cell type-specific transcriptomes. Here we show that the RNA-associated protein Srrt/Ars2 sustains embryonic stem...

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Detalles Bibliográficos
Autores principales: Kainov, Yaroslav A., Makeyev, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969169/
https://www.ncbi.nlm.nih.gov/pubmed/31953406
http://dx.doi.org/10.1038/s41467-019-14204-z