Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway

Myocardial hypertrophy, an inflammatory condition of cardiac muscles is a maladaptive response of the heart to biomechanical stress, hemodynamic or neurohormonal stimuli. Previous studies indicated that knockout of Arginyltransferase (ATE1) gene in mice and embryos leads to contractile dysfunction,...

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Detalles Bibliográficos
Autores principales: Singh, Kanika, Gupta, Ankit, Sarkar, Ashish, Gupta, Ishita, Rana, Santanu, Sarkar, Sagartirtha, Khan, Sameena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969214/
https://www.ncbi.nlm.nih.gov/pubmed/31953451
http://dx.doi.org/10.1038/s41598-019-57379-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969214/
https://www.ncbi.nlm.nih.gov/pubmed/31953451
http://dx.doi.org/10.1038/s41598-019-57379-7

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