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Early-life stress, microbiota, and brain development: probiotics reverse the effects of maternal separation on neural circuits underpinning fear expression and extinction in infant rats

Early-life stress has pervasive, typically detrimental, effects on physical and mental health across the lifespan. In rats, maternal-separation stress results in premature expression of an adult-like profile of fear regulation that predisposes stressed rats to persistent fear, one of the hallmarks o...

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Detalles Bibliográficos
Autores principales: Cowan, Caitlin S.M., Stylianakis, Anthea A., Richardson, Rick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969299/
https://www.ncbi.nlm.nih.gov/pubmed/30981894
http://dx.doi.org/10.1016/j.dcn.2019.100627