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Early-life stress, microbiota, and brain development: probiotics reverse the effects of maternal separation on neural circuits underpinning fear expression and extinction in infant rats
Early-life stress has pervasive, typically detrimental, effects on physical and mental health across the lifespan. In rats, maternal-separation stress results in premature expression of an adult-like profile of fear regulation that predisposes stressed rats to persistent fear, one of the hallmarks o...
Autores principales: | Cowan, Caitlin S.M., Stylianakis, Anthea A., Richardson, Rick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969299/ https://www.ncbi.nlm.nih.gov/pubmed/30981894 http://dx.doi.org/10.1016/j.dcn.2019.100627 |
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