Microglial depletion and repopulation in brain slice culture normalizes sensitized proinflammatory signaling

BACKGROUND: Microglia are critical mediators of neuroimmune pathology across multiple neurologic disorders. Microglia can be persistently activated or “primed” by Toll-like receptor (TLR) activation, ethanol, stress, and other insults. Thus, strategies to prevent or reverse microglial priming may be...

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Detalles Bibliográficos
Autores principales: Coleman, Leon G., Zou, Jian, Crews, Fulton T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969463/
https://www.ncbi.nlm.nih.gov/pubmed/31954398
http://dx.doi.org/10.1186/s12974-019-1678-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969463/
https://www.ncbi.nlm.nih.gov/pubmed/31954398
http://dx.doi.org/10.1186/s12974-019-1678-y

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