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Microglial depletion and repopulation in brain slice culture normalizes sensitized proinflammatory signaling
BACKGROUND: Microglia are critical mediators of neuroimmune pathology across multiple neurologic disorders. Microglia can be persistently activated or “primed” by Toll-like receptor (TLR) activation, ethanol, stress, and other insults. Thus, strategies to prevent or reverse microglial priming may be...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969463/ https://www.ncbi.nlm.nih.gov/pubmed/31954398 http://dx.doi.org/10.1186/s12974-019-1678-y |