Proteome-wide observation of the phenomenon of life on the edge of solubility

To function effectively proteins must avoid aberrant aggregation, and hence they are expected to be expressed at concentrations safely below their solubility limits. By analyzing proteome-wide mass spectrometry data of Caenorhabditis elegans, however, we show that the levels of about three-quarters...

Descripción completa

Detalles Bibliográficos
Autores principales: Vecchi, Giulia, Sormanni, Pietro, Mannini, Benedetta, Vandelli, Andrea, Tartaglia, Gian Gaetano, Dobson, Christopher M., Hartl, F. Ulrich, Vendruscolo, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969518/
https://www.ncbi.nlm.nih.gov/pubmed/31892536
http://dx.doi.org/10.1073/pnas.1910444117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969518/
https://www.ncbi.nlm.nih.gov/pubmed/31892536
http://dx.doi.org/10.1073/pnas.1910444117

Ejemplares similares