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The proton electrochemical gradient induces a kinetic asymmetry in the symport cycle of LacY
LacY catalyzes accumulation of galactosides against a concentration gradient by coupling galactoside and H(+) transport (i.e., symport). While alternating access of sugar- and H(+)-binding sites to either side of the membrane is driven by binding and dissociation of sugar, the electrochemical H(+) g...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969543/ https://www.ncbi.nlm.nih.gov/pubmed/31889006 http://dx.doi.org/10.1073/pnas.1916563117 |