Cargando…
The proton electrochemical gradient induces a kinetic asymmetry in the symport cycle of LacY
LacY catalyzes accumulation of galactosides against a concentration gradient by coupling galactoside and H(+) transport (i.e., symport). While alternating access of sugar- and H(+)-binding sites to either side of the membrane is driven by binding and dissociation of sugar, the electrochemical H(+) g...
Autores principales: | Jiang, Xiaoxu, Ermolova, Natalia, Lim, John, Choi, Seo Woo, Kaback, H. Ronald |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969543/ https://www.ncbi.nlm.nih.gov/pubmed/31889006 http://dx.doi.org/10.1073/pnas.1916563117 |
Ejemplares similares
-
Galactoside-Binding Site in LacY
por: Jiang, Xiaoxu, et al.
Publicado: (2014) -
The Alternating Access Transport Mechanism in LacY
por: Kaback, H. Ronald, et al.
Publicado: (2010) -
Diversity in kinetics correlated with structure in nano body-stabilized LacY
por: Kumar, Hemant, et al.
Publicado: (2020) -
Function Trumps Form in Two Sugar Symporters, LacY and vSGLT
†
por: Abramson, Jeff, et al.
Publicado: (2021) -
Enhancement of LacI binding in vivo
por: Du, Manyu, et al.
Publicado: (2019)