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PHLPP Sensitizes Multiple Myeloma Cells to Bortezomib Through Regulating LAMP2
INTRODUCTION: Treatment of bortezomib (BTZ) improves the clinical outcomes of patients with multiple myeloma (MM). However, primary resistance and acquired resistance to BTZ frequently develop in patients with MM. PH domain leucine-rich repeat protein phosphatase (PHLPP) plays an important role in c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969690/ https://www.ncbi.nlm.nih.gov/pubmed/32021285 http://dx.doi.org/10.2147/OTT.S237343 |