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Glucocorticoid Receptor α Mediates Roflumilast’s Ability to Restore Dexamethasone Sensitivity in COPD

BACKGROUND: Glucocorticoids are commonly prescribed to treat inflammation of the respiratory system; however, they are mostly ineffective for controlling chronic obstructive pulmonary disease (COPD)-associated inflammation. This study aimed to elucidate the molecular mechanisms responsible for such...

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Detalles Bibliográficos
Autores principales: Reddy, Aravind T, Lakshmi, Sowmya P, Banno, Asoka, Reddy, Raju C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969699/
https://www.ncbi.nlm.nih.gov/pubmed/32021151
http://dx.doi.org/10.2147/COPD.S230188