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Bacteroides fragilis enterotoxin upregulates heme oxygenase-1 in dendritic cells via reactive oxygen species-, mitogen-activated protein kinase-, and Nrf2-dependent pathway

BACKGROUND: Enterotoxigenic Bacteroides fragilis (ETBF) causes colitis and diarrhea, and is considered a candidate pathogen in inflammatory bowel diseases as well as colorectal cancers. These diseases are dependent on ETBF-secreted toxin (BFT). Dendritic cells (DCs) play an important role in directi...

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Detalles Bibliográficos
Autores principales: Ko, Su Hyuk, Jeon, Jong Ik, Woo, Hyun Ae, Kim, Jung Mogg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969884/
https://www.ncbi.nlm.nih.gov/pubmed/31988590
http://dx.doi.org/10.3748/wjg.v26.i3.291