Combined Modality Therapy Based on Hybrid Gold Nanostars Coated with Temperature Sensitive Liposomes to Overcome Paclitaxel-Resistance in Hepatic Carcinoma

In this study, we prepared gold nanostar (GNS) composite nanoparticles containing siRNA of cyclooxygenase-2(siCOX-2) that were modified by tumor targeting ligand 2-deoxyglucose (DG) and transmembrane peptide 9-poly-D-arginine (9R) to form siCOX-2(9R/DG-GNS). Paclitaxel loaded temperature sensitive l...

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Detalles Bibliográficos
Autores principales: Zhu, Hongyan, Han, Weili, Gan, Ye, Li, Qiaofeng, Li, Xiaolan, Shao, Lanlan, Zhu, Dan, Guo, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969923/
https://www.ncbi.nlm.nih.gov/pubmed/31847496
http://dx.doi.org/10.3390/pharmaceutics11120683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969923/
https://www.ncbi.nlm.nih.gov/pubmed/31847496
http://dx.doi.org/10.3390/pharmaceutics11120683

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