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Combined Modality Therapy Based on Hybrid Gold Nanostars Coated with Temperature Sensitive Liposomes to Overcome Paclitaxel-Resistance in Hepatic Carcinoma
In this study, we prepared gold nanostar (GNS) composite nanoparticles containing siRNA of cyclooxygenase-2(siCOX-2) that were modified by tumor targeting ligand 2-deoxyglucose (DG) and transmembrane peptide 9-poly-D-arginine (9R) to form siCOX-2(9R/DG-GNS). Paclitaxel loaded temperature sensitive l...
Autores principales: | Zhu, Hongyan, Han, Weili, Gan, Ye, Li, Qiaofeng, Li, Xiaolan, Shao, Lanlan, Zhu, Dan, Guo, Hongwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969923/ https://www.ncbi.nlm.nih.gov/pubmed/31847496 http://dx.doi.org/10.3390/pharmaceutics11120683 |
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