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Structural and Dynamic Characterizations Highlight the Deleterious Role of SULT1A1 R213H Polymorphism in Substrate Binding

Sulfotransferase 1A1 (SULT1A1) is responsible for catalyzing various types of endogenous and exogenous compounds. Accumulating data indicates that the polymorphism rs9282861 (R213H) is responsible for inefficient enzymatic activity and associated with cancer progression. To characterize the detailed...

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Detalles Bibliográficos
Autores principales: Dash, Raju, Ali, Md. Chayan, Dash, Nayan, Azad, Md. Abul Kalam, Hosen, S. M. Zahid, Hannan, Md. Abdul, Moon, Il Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6969939/
https://www.ncbi.nlm.nih.gov/pubmed/31835852
http://dx.doi.org/10.3390/ijms20246256