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Promoter polymorphisms of TOP2A and ERCC1 genes as predictive factors for chemotherapy in non‐small cell lung cancer patients

BACKGROUND: Topoisomerase 2‐alpha (TOP2A) is an enzyme that controls topologic changes in DNA during transcription and replication. ERCC1 is an enzyme that takes part in DNA repair processes. The purpose of this study was to assess the predictive role of particular single nucleotide polymorphisms (S...

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Detalles Bibliográficos
Autores principales: Grenda, Anna, Błach, Justyna, Szczyrek, Michał, Krawczyk, Paweł, Nicoś, Marcin, Kuźnar Kamińska, Barbara, Jakimiec, Monika, Balicka, Grażyna, Chmielewska, Izabela, Batura‐Gabryel, Halina, Sawicki, Marek, Milanowski, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970032/
https://www.ncbi.nlm.nih.gov/pubmed/31797573
http://dx.doi.org/10.1002/cam4.2743