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Reduced PLCG1 expression is associated with inferior survival for myelodysplastic syndromes

The PLCG1 gene, which encodes the phospholipase C γ1 isoform, is located within the commonly deleted region of the long arm of chromosome 20 (del(20q)) observed in myelodysplastic syndromes (MDS). Phospholipase C is involved in diverse physiological and pathological cellular processes through inosit...

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Detalles Bibliográficos
Autores principales: Shiseki, Masayuki, Ishii, Mayuko, Miyazaki, Mari, Osanai, Satoko, Wang, Yan‐Hua, Yoshinaga, Kentaro, Mori, Naoki, Tanaka, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6970055/
https://www.ncbi.nlm.nih.gov/pubmed/31755660
http://dx.doi.org/10.1002/cam4.2717